Inspector Gadget is a clumsy, dim-witted human cyborg detective with various bionic gadgets built into his body. Gadget stumbles around working the cases while his niece and dog do most of the investigating. Gadget's arch-nemesis is Dr. Claw, the leader of an evil organisation, known as "M.A.D."
Penny teams up with a Tibetan boy to destroy a M.A.D. weather control machine while her uncle blunders around as usual.
Gadget must put a stop to M.A.D.'s latest plot for global domination, which involves the kidnapping of the world's leading solar scientists and coercing them to design and construct a solar-powered heat cannon at the grounds of mysterious Stonehenge.
A M.A.D. agent intends to use his pet snakes to steal a valuable coin collection.
In Paris a M.A.D. agent uses a robot to rob the rich and famous.
Dr. Claw has concocted a chemical compound that decomposes wood at an accelerated rate, which he threatens to unleash upon the world's forests in exchange for a hefty ransom.
In Turkey a M.A.D. agent uses his birds to steal a very valuable gemstone from an exhibition.
