Based on the blockbuster films, this action-packed animated series starts a decade after the original Ghostbusters saved New York City from ghosts, goblins and ghouls. All the guys have left town, except Egon, now teaching a Paranormal Studies class at the local university. But Zuul, the all-powerful demon, has awakened from hibernation to wreak havoc on the unsuspecting masses. Desperate to recruit a new team, Egon and the plucky Janine turn to four of his teenage students: Kylie, a genius with an encyclopedic knowledge of the occult; Eduardo, a hip slacker with a crush on Kylie; Garrett, a wheelchair-bound athlete with a hot temper; and Roland, a “gentle giant” mechanical whiz. It's only a matter of time before Egon, Janine, old pal Slimer and the “kids” band together to rid the city of the evildoers.
The EGB are on a job to bust a ghost, when they find the ghost is the house they're in and intent making two trapped children it's next meal.
Ghostly clowns are on the loose and feeding on laughter. Eduardo traps one of them, but then he starts to turn into one of them.
Everytime someone looks at the strange orb, a ghost appears to steal their eyes. Problem is, a museum is about to put the orb on display.
Janine attempts to make Egon jealous by going on a date with another man. Unfortunately, the man she dates is a bug demon in disguise and looking for a queen.
Ghosts are rampaging through the city and the EGB's equipment can't stop them. But a mysterious Piper claims he can.
A ghost capable of granting wishes comes to town in the form of a salesman, only his results are far from what people wanted. Eduardo unfortunately becomes his latest victim when he gets placed inside Kylie's cat.
