When Reed Richards, Sue and Johnny Storm and pilot Ben Grimm take a premature space flight on a new shuttle, they find themselves massively bombarded with cosmic radiation. Barely managing to re-enter and land safely, the quartet find themselves forever transformed with superpowers. Deciding to use these new powers to help people, they form the Fantastic Four, a superhero team dedicated to the protection of Earth from menaces like the Latverian King Dr. Doom and Galactus, the planet consumer.
As Galactus' plans unfold, the Fantastic Four try to reason with him, but it proves futile. The only way to defeat Galactus now, puts Johnny's life in mortal danger. Meanwhile, the Silver Surfer sees Alicia and his loyalties begin to change.
The Skrulls let loose a new danger for the Fantastic Four to face, a being that possesses their combined powers: Super Skrull! Will the team be able to take this villain down?
Doctor Doom has captured the Fanastic Four, taking them to his treacherous castle.
Sue learns about Doctor Doom's past, while the others deal with the castle's traps. When they find him, Doom offers a deal: travel back in time to retrieve an ancient casket or Sue will be killed.
Reed, Johnny, and Ben arrive in ancient Greece, with only forty-eight hours to find the casket. Their problems multiply, however, when they get into the middle of the Battle of Thermopalye.
The Fantastic Four are at a charity function at Rockefeller Center, when the building is dragged underground. It's discovered that the Mole Man is responsible and he plans for world domination.
