Inspector Gadget is a clumsy, dim-witted human cyborg detective with various bionic gadgets built into his body. Gadget stumbles around working the cases while his niece and dog do most of the investigating. Gadget's arch-nemesis is Dr. Claw, the leader of an evil organisation, known as "M.A.D."
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Dr. Claw intends to sink most of an island so that his (currently) mountaintop resort will become the only hotel on "M.A.D. Island".
M.A.D. has enlisted the aid of the incarcerated Funny Money counterfeiting gang in a plot to generate millions upon millions of bogus dollars for Dr. Claw to use in his dirty work. Two of the gang's three members manage to escape from prison in order to set up shop, while the last and most talented member, a visually-challenged man named Squint, must be up to the arduous task of bumping off Gadget when he comes to the jail to investigate the break-out.
Dr. Claw begins making US Airforce jets disappear so that he can create his own private M.A.D. airforce.
A M.A.D. agent and his Blue Trolls causes a drought in Metro City by cutting off the city's mountain water resources.
Dr. Claw creates a ray that turns gold into smelly cheese, planning to change it back once the government empties Fort Knox of the foul smelling stuff.
Gadget is assigned to protect "Nervous Nick" Defecto, a former M.A.D. agent, from Dr. Claw's wrath. In revenge, Dr. Claw takes Chief Quimby hostage and offers him in exchange for his wayward agent.
